細胞名稱

小鼠雜交瘤細胞OKT3

貨物編碼

BFN60806665

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研           3類

培養(yǎng)體系

DMEM高糖+10%FBS+1%雙抗

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

小鼠雜交瘤細胞OKT3懸浮培養(yǎng)。該細胞源于ECACC

序列突變

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注釋

Characteristics: The monoclonal antibody produced by this hybridoma was used as an immunosuppressant drug under the name Muromonab-CD3 (Orthoclone OKT3).

Characteristics: The monoclonal antibody produced by this hybridoma was used to prepare the humanized MGA031 (Teplizumab) therapeutic antibody.

Monoclonal antibody isotype: IgG2a.

Monoclonal antibody target: UniProtKB; P07766; Human CD3E.

Anecdotal: OKT3 was the first monoclonal antibody to be approved for clinical use in humans.

STR信息

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參考文獻

PubMed=314668; DOI=10.1126/science.314668

Kung P.C., Goldstein G., Reinherz E.L., Schlossman S.F.

Monoclonal antibodies defining distinctive human T cell surface antigens.

Science 206:347-349(1979)

Patent=US4361549

Kung P.C., Goldstein G.

Complement-fixing monoclonal antibody to human T cells, and methods of preparing same.

Patent number US4361549, 30-Nov-1982